Proteomics

Dataset Information

0

Aging-Associated Changes in CSF Protein Abundances and Structures Revealed by a Modified LiP-MS Screen


ABSTRACT: We performed LiP-MS on CSF from young and old mice with a modified analysis pipeline. We found 38 protein groups that change in abundance with aging, most dominantly immunoglobulins of the IgM subclass. We discovered six high-confidence candidates that appeared to change in structure with aging.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cerebrospinal Fluid

SUBMITTER: Steven Shuken  

LAB HEAD: Tony Wyss-Coray

PROVIDER: PXD031174 | Pride | 2022-08-22

REPOSITORIES: Pride

Similar Datasets

2022-08-18 | PXD035825 | Pride
2018-04-23 | PXD008974 | Pride
2022-08-18 | PXD035871 | Pride
2023-10-24 | PXD041061 | Pride
2007-12-20 | E-GEOD-272 | biostudies-arrayexpress
2021-03-04 | PXD024488 | Pride
2023-07-19 | PXD043613 | Pride
2021-01-07 | PXD019272 | Pride
2012-02-01 | E-GEOD-34476 | biostudies-arrayexpress
2012-10-01 | E-GEOD-33063 | biostudies-arrayexpress