Proteomics

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Effects of non-thermal methods (High-Pressure Processing, UV-C irradiation and thermoultrasonication) on donor human milk safety and functionality


ABSTRACT: This study was conducted in order to evaluate the effects of high-pressure processing, UV-C irradiation and thermo-ultrasonication on donor human milk safety and quality. The results of these methods were then compared with holder pasteurization, which is the current recommended treatment for donor human milk.

INSTRUMENT(S): LTQ Orbitrap XL, Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Milk

SUBMITTER: Sjef Boeren  

LAB HEAD: Sjef Boeren

PROVIDER: PXD031216 | Pride | 2022-03-11

REPOSITORIES: Pride

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Publications

Effects of High-Pressure Processing, UV-C Irradiation and Thermoultrasonication on Donor Human Milk Safety and Quality.

Kontopodi Eva E   Stahl Bernd B   van Goudoever Johannes B JB   Boeren Sjef S   Timmermans Rian A H RAH   den Besten Heidy M W HMW   Van Elburg Ruurd M RM   Hettinga Kasper K  

Frontiers in pediatrics 20220321


Holder pasteurization (HoP) is the current recommended treatment for donor human milk. Although this method inactivates microbial contaminants, it also negatively affects various milk components. High-pressure processing (HPP, 400, 500, and 600 MPa), ultraviolet-C irradiation (UV-C, 2,430, 3,645, and 4,863 J/L) and thermoultrasonication (TUS, 1,080 and 1,620 kJ/L) were investigated as alternatives to thermal pasteurization (HoP). We assessed the effects of these methods on microbiological safety  ...[more]

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