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Post-covid surgical complications in adipose tissue

ABSTRACT: Spinal cord injury (SCI) patients who underwent reconstructive surgery for pressure ulcers (PU) within 4 weeks of positive SARS-CoV-2 diagnosis were included in this study. Patient’s post-operative progression was registered, while the adipose tissue surrounding the ulcers was analyzed by proteomic and immunohistochemical assays to identify molecular/cellular signatures of impaired recovery.

INSTRUMENT(S): TripleTOF 6600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): White Adipose Tissue

SUBMITTER: Carmen Duran

LAB HEAD: Carmen Duran-Ruiz

PROVIDER: PXD031241 | Pride | 2022-05-20

REPOSITORIES: Pride

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Post-COVID Complications after Pressure Ulcer Surgery in Patients with Spinal Cord Injury Associate with Creatine Kinase Upregulation in Adipose Tissue.

Martínez-Torija Mario M Esteban Pedro F PF Espino-Rodríguez Francisco Javier FJ Paniagua-Torija Beatriz B Molina-Holgado Eduardo E Ceruelo Silvia S Barroso-Garcia Gemma G Arandilla Alba G AG Lopez-Almodovar Luis F LF Arevalo-Martin Angel A Moreno Juan Antonio JA Garcia-Ovejero Daniel D Durán-Ruiz Mª Carmen MC Moreno-Luna Rafael R

Cells 20220409 8

The risk of complications following surgical procedures is significantly increased in patients with SARS-CoV-2 infection. However, the mechanisms underlying these correlations are not fully known. Spinal cord injury (SCI) patients who underwent reconstructive surgery for pressure ulcers (PUs) before and during the COVID-19 pandemic were included in this study. The patient's postoperative progression was registered, and the subcutaneous white adipose tissue (s-WAT) surrounding the ulcers was anal ...[more]

PMID: 35455962

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