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Human, gastric cancer line, LC-MSMS

ABSTRACT: We also tested the downstream differentiation of protein expression between BGC823 Ctrl and BGC823 MIR137HG by IP target FUS following LC-MS/MS. And we selected several proteins related to tumor growth and metastasis to analyze further. String data showed that they might have more contact with each other. Western blot data showed that MET, CTNNB1 and RHOC were also co-expressed with the over-expression MIR137HG.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Cell Type Cancer

SUBMITTER: Yantao Du

LAB HEAD: Yantao Du

PROVIDER: PXD031258 | Pride | 2022-08-12

REPOSITORIES: Pride

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miR-2682-3p antagonizes its host lncRNA-MIR137HG by interacting with the same target FUS to regulate the progression of gastric cancer.

Du Yantao Y Chen Yichen Y Wu Tao T Fan Xiaodan X Lin Wei W Jiang Zhouhua Z

BMC cancer 20220622 1

<h4>Background</h4>The mechanism of long non-coding RNA MIR137HG in human gastric cancer (GC) is currently unknown. In the present study, we aimed to explore the function and mechanism of MIR137HG in gastric cancer.<h4>Methods</h4>The expression of lncRNA-MIR137HG in 69 gastric cancer samples and their paired surgical margin (SM) tissue samples were tested by QRT-PCR. UCSC was used to find the gene location relationship among MIR137HG and its embedded miRNAs. TargetScan was used to predict the t ...[more]

PMID: 35733138

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