Dataset Information
LUBAC interactors identification
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Federico Uliana
LAB HEAD: Federico Uliana
PROVIDER: PXD031520 | Pride | 2022-10-14
REPOSITORIES: Pride
Publications
Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.
Proceedings of the National Academy of Sciences of the United States of America 20220930 40
Protein-protein interactions (PPIs) represent the main mode of the proteome organization in the cell. In the last decade, several large-scale representations of PPI networks have captured generic aspects of the functional organization of network components but mostly lack the context of cellular states. However, the generation of context-dependent PPI networks is essential for structural and systems-level modeling of biological processes-a goal that remains an unsolved challenge. Here we describ ...[more]