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Global proteome of Atg16L1flox:CAG-CreTmx WT and KO neurons

ABSTRACT: The experiment was performed to identify autophagy targets in wildtype and autophagy-deficient primary neurons. Therefore, cortico-hippocampal neurons were isolated from Atg16L1flox:CAG-CreTmx mice and treated with Tamoxifen (Tmx) to induce the knockout (KO) or EtOH for wildtype (WT) in-vitro. WT and KO Neurons were harvested at day in-vitro (DIV) 15-16, and global proteome analysis was measured by LC-MS/MS.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Hippocampal Neuron

SUBMITTER: Prerana Wagle

LAB HEAD: N.L. Kononenko

PROVIDER: PXD031555 | Pride | 2022-11-15

REPOSITORIES: Pride

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