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SAPP a neuroprotective protein in the brain has widespread effects on the proteome of human cortical neurons related to memory mechanisms.

ABSTRACT: Human glutamatergic neurons in culture were exposed to 1 nM secreted amyloid precursor protein alpha over a time course (0, 2, 6 and 24 h) and changes in the proteome were identified with SWATH-MS.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cns Neuron (sensu Vertebrata)

DISEASE(S): Alzheimer's Disease

SUBMITTER: Torsten Kleffmann

LAB HEAD: Warren Tate

PROVIDER: PXD031704 | Pride | 2022-04-03

REPOSITORIES: Pride

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