Proteomics

Dataset Information

0

Proteomic analysis of small extracellular vesicles (sEVs) derived from primary keratinocytes cultured in different calcium concentrations, treated with a peanut allergen extract and atopic dermatitis (AD)-relevant cytokines


ABSTRACT: Epidermal keratinocytes are key for maintenance of the integrity of the epidermis. One of the main drivers of keratinocyte differentiation is the calcium gradient; calcium concentration gradually increases towards the outer layers of the epidermis. Atopic dermatitis (AD) is a disorder associated with a chronic inflammatory state and a compromised epidermal barrier. Keratinocytes secrete lipid-rich small extracellular vesicles (sEVs) that acts as mediators of both local and long-distance signaling.

INSTRUMENT(S): TripleTOF 5600+

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Keratinocyte

DISEASE(S): Atopic Dermatitis,Hypersensitivity Reaction Type I Disease

SUBMITTER: Paulina Czaplewska  

LAB HEAD: Paulina Czaplewska

PROVIDER: PXD031729 | Pride | 2022-06-07

REPOSITORIES: Pride

Similar Datasets

2022-10-04 | PXD025431 | Pride
2015-12-15 | E-GEOD-59275 | biostudies-arrayexpress
2016-11-13 | GSE72449 | GEO
2021-06-08 | GSE176279 | GEO
2015-07-31 | E-GEOD-68723 | biostudies-arrayexpress
2015-07-31 | E-GEOD-68725 | biostudies-arrayexpress
2015-07-31 | E-GEOD-68724 | biostudies-arrayexpress
2006-12-23 | GSE6601 | GEO
2011-09-19 | E-GEOD-30355 | biostudies-arrayexpress
2015-12-15 | GSE59275 | GEO