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Paleoproteomics of ancient human teeth

ABSTRACT: Teeth are a well-known source of information for paleoanthropologists. Here, we established the ancient dental metaproteomes in several samples from historic sites. The shotgun metaproteomics analysis relies on a iterative search strategy for the identification of the proteins and their origins.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human) Archaea Viruses Bacteria Eukaryota (eucaryotes)

TISSUE(S): Tooth

SUBMITTER: Jean ARMENGAUD

LAB HEAD: Jean Armengaud

PROVIDER: PXD031786 | Pride | 2023-03-30

REPOSITORIES: Pride

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An ancient coronavirus from individuals in France, circa 16th century.

Oumarou Hama Hamadou H Chenal Thomas T Pible Olivier O Miotello Guylaine G Armengaud Jean J Drancourt Michel M

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20230315

<h4>Objectives</h4>At the time when the COVID-19 pandemic was responsible for more than six million deaths worldwide, the antiquity of coronaviruses remains undefined. We investigated individuals buried during the 16th century in France for the direct and paleoserological diagnosis of the coronavirus.<h4>Methods</h4>The 2011-2012 excavation of Abbey Saint-Pierre in Baume-Les-Messieurs, France uncovered 12 skeletons of individuals from the 13th to the 18th century. The total proteins extracted fr ...[more]

PMID: 36924840

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