Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Gastric Adenocarcinoma Cell, Diploid Cell
DISEASE(S): Gastric Adenocarcinoma
SUBMITTER: Aditi Chatterjee
LAB HEAD: Aditi chatterjee
PROVIDER: PXD032001 | Pride | 2022-06-09
REPOSITORIES: Pride
Frontiers in genetics 20220513
Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) is a serine/threonine protein kinase which functions <i>via</i> the calcium-triggered signaling cascade with CAMK1, CAMK4, and AMPKα as the immediate downstream substrates. CAMKK2 is reported to be overexpressed in gastric cancer; however, its signaling mechanism is poorly understood. We carried out label-free quantitative tyrosine phosphoproteomics to investigate tyrosine-mediated molecular signaling associated with CAMKK2 in gastric ...[more]