Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Pancreas
DISEASE(S): Pancreatic Ductal Adenocarcinoma
SUBMITTER: Antje Dittmann
LAB HEAD: Jamie Feliu
PROVIDER: PXD032076 | Pride | 2022-06-21
REPOSITORIES: Pride
Cancers 20220513 10
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with an overall 5-year survival rate of just 5%. A better understanding of the carcinogenesis processes and the mechanisms of the progression of PDAC is mandatory. Fifty-two PDAC patients treated with surgery and adjuvant therapy, with available primary tumors, normal tissue, preneoplastic lesions (PanIN), and/or lymph node metastases, were selected for the study. Proteins were extracted from small punches and analyzed by LC-MS/MS ...[more]