Tissue Catabolism and Donor-Specific Dexamethasone Response in a Human Osteochondral Model of Post-Traumatic Osteoarthritis

ABSTRACT: We present an ex vivo human osteochondral model of PTOA to investigate disease effects on catabolism and cellular homeostasis in a multi-tissue system and discover biomarkers for disease progression and drug efficacy.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Ankle Joint, Articular Cartilage, Bone

DISEASE(S): Osteoarthritis

SUBMITTER: Patrik Onnerfjord  

LAB HEAD: Patrik Önnerfjord

PROVIDER: PXD032213 | Pride | 2022-08-12

REPOSITORIES: Pride