Higher dimensional cross-linking with a tetra-reactive cross-linker

ABSTRACT: A tetrameric CID-cleavable cross-linker was synthesized and applied to BSA and isolated mitochondria from mouse hearts. A real-time instrument method was developed to dynamically target released peptides from cross-linked species, enabling their characterization through a series of ms3 scans.

INSTRUMENT(S):

ORGANISM(S): Bos Taurus (bovine) Mus Musculus (mouse)

TISSUE(S): Heart

SUBMITTER: Jared Mohr  

LAB HEAD: James Bruce

PROVIDER: PXD032222 | Pride | 2023-11-27

REPOSITORIES: Pride