Mouse and human abdominal aneurysm proteomics

ABSTRACT: Aortic tissues of developing and established aneurysms produced by angiotensin II (AngII) infusion were examined in Apoe-/- and Ldlr-/- mice. Aortas were also acquired from wildtype C57BL/6J mice following intraluminal elastase incubation. Aortas were dissected free and separated into eight anatomical segments for proteomics in comparison to their appropriate controls. In addition, proteomics was performed on human infrarenal aortic aneurysm tissues as well as aortic tissue collected from age-matched controls.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Abdominal Aorta, Aortic Smooth Muscle Cell

DISEASE(S): Abdominal Aortic Aneurysm

SUBMITTER: Sasha Singh  

LAB HEAD: Masanori Aikawa

PROVIDER: PXD032293 | Pride | 2022-08-02

REPOSITORIES: Pride