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DIA Quantification Proteomics of rat tissues including bph and sham rats

ABSTRACT: In this project, Q-Exactive HF(Thermo Fisher Scientific,San Jose,CA) was used to acquire mass spectrometry (MS) data for 7 samples in Data Independent Acquisition (DIA) mode. Quantification of peptides and proteins was performed using Spectronaut™ and MSstats software packages

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Prostate Gland, Epithelial Cell

DISEASE(S): Prostatic Hypertrophy

SUBMITTER: jiamin gu

LAB HEAD: Zeng Xiantao

PROVIDER: PXD032395 | Pride | 2025-12-01

REPOSITORIES: Pride

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			Action	DRS
	19P12420001.raw	Raw
	19P12420002.raw	Raw
	19P12420003.raw	Raw
	19P12420004.raw	Raw
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Publications

Mitogen-activated protein kinase pathway and four genes involved in the development of benign prostatic hyperplasia: <i>in vivo</i> and <i>vitro</i> validation.

Gu Jia-Min JM Guo Xing-Pei XP Wu Lan L Li Lu-Yao LY Zhu Cong C Deng Tong T Wang Shuang-Ying SY Fang Cheng C Zeng Xian-Tao XT

Frontiers in immunology 20251111

<h4>Background</h4>Benign prostatic hyperplasia (BPH) is a common age-associated disorder characterized by non-malignant proliferation of prostate tissues. However, its underlying molecular mechanisms remain incompletely elucidated.<h4>Methods</h4>A rat model of BPH was established via surgical castration followed by testosterone propionate administration. Proteomic profiling was performed on prostate tissues from BPH and sham-operated rats. Public datasets of BPH patients and healthy individual ...[more]

PMID: 41306978

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