FAM134B oligomer ubiquitination and ER-phagy

ABSTRACT: FAM134B is a reticulon-homology domain (RHD)-containing protein that participates in membrane-shaping of the endoplasmic reticulum (ER)8 13. It also functions as a mammalian ER-phagy receptor, mediating the fragmentation and selective degradation of ER sheets in multiple cell types8. However, little is known about the molecular and biophysical mechanisms that control and/or switch between these two FAM134B functions.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell

SUBMITTER: Adriana Covarrubias-Pinto  

LAB HEAD: Ivan Dikic

PROVIDER: PXD032741 | Pride | 2023-06-19

REPOSITORIES: Pride