Proteomics

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Label-free proteomics test on TGF-β1-induced human mesothelial cell (Met5A) treated with or without Fushen Granule


ABSTRACT: Fushen Granule (FSG), a Chinese medicinal formular, was clinically used to improve the peritoneal dialysis (PD) efficiency in ESRD patients received PD treatment. However, its mechanisms of anti-fibrotic effect in peritoneal fibrosis (PF) has not been studied yet. In this work, we used TGF-β1-stimulated MeT5A cells to mimic the process of PF in vitro, and Label-free proteomics and bioinformatics analysis were used to explored the underlying targets and pathways of FSG on TGF-β1-treated MeT5A cells

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Kang Yang  

LAB HEAD: Hongtao Yang

PROVIDER: PXD033058 | Pride | 2022-04-20

REPOSITORIES: Pride

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