Label-free proteomics test on TGF-β1-induced human mesothelial cell (Met5A) treated with or without Fushen Granule
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ABSTRACT: Fushen Granule (FSG), a Chinese medicinal formular, was clinically used to improve the peritoneal dialysis (PD) efficiency in ESRD patients received PD treatment. However, its mechanisms of anti-fibrotic effect in peritoneal fibrosis (PF) has not been studied yet. In this work, we used TGF-β1-stimulated MeT5A cells to mimic the process of PF in vitro, and Label-free proteomics and bioinformatics analysis were used to explored the underlying targets and pathways of FSG on TGF-β1-treated MeT5A cells
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Kang Yang
LAB HEAD: Hongtao Yang
PROVIDER: PXD033058 | Pride | 2022-04-20
REPOSITORIES: Pride
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