Multi-omics approach to characterize sex-specific metabolic alterations in triple-transgenic Alzheimer's mouse brain

ABSTRACT: We aimed to characterise alterations in metabolic pathways and proteome composition in a mouse model of Alzheimer disease (AD). We specifically aimed to evaluate how these differences may be sex-specific by integrative multi-omics analysis (metabolites, lipids, proteins).

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

DISEASE(S): Alzheimer's Disease

SUBMITTER: Manfredo Quadroni  

LAB HEAD: Julijana Ivanisevic

PROVIDER: PXD033164 | Pride | 2023-03-11

REPOSITORIES: Pride