Proteomics

Dataset Information

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Core fucosylation in mesenchymal glioblastoma


ABSTRACT: Glycoproteomic screening indicates that core fucosylation activation is more highly enhancedin mesenchymal (MES) than in proneural (PN) glioblastoma cancer stem cells (GSCs) and this pattern is retained in subgroup-specific xenograftsand human patients’ samples. Most MES-restricted core fucosylated proteins are involved in therapeutically relevant pathological processes, such as extracellular matrix interaction and tumor invasion.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Stem Cell, Cell Culture

DISEASE(S): Brain Cancer

SUBMITTER: Annapaola Andolfo  

LAB HEAD: Rossella Galli

PROVIDER: PXD033408 | Pride | 2022-11-09

REPOSITORIES: Pride

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