Core fucosylation in mesenchymal glioblastoma
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ABSTRACT: Glycoproteomic screening indicates that core fucosylation activation is more highly enhancedin mesenchymal (MES) than in proneural (PN) glioblastoma cancer stem cells (GSCs) and this pattern is retained in subgroup-specific xenograftsand human patients’ samples. Most MES-restricted core fucosylated proteins are involved in therapeutically relevant pathological processes, such as extracellular matrix interaction and tumor invasion.
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Stem Cell, Cell Culture
DISEASE(S): Brain Cancer
SUBMITTER: Annapaola Andolfo
LAB HEAD: Rossella Galli
PROVIDER: PXD033408 | Pride | 2022-11-09
REPOSITORIES: Pride
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