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Immunoproteome profiling of Listeria monocytogenes under mild acid and salt stress conditions

ABSTRACT: Listeria monocytogenes is the ubiquitous food-borne pathogen which causes listeriosis, a disease with a high mortality rate, mostly transmitted through contaminated ready-to-eat foods (EFSA, 2018). To better understand the systemic response of such microorganism exposed at three environmental factors (T, pH and NaCl), the proteome of a L. monocytogenes strain, which was isolated from a meat product (Coppa di testa) linked to a listeriosis outbreak occurred in Marche region (Italy) in 2016, was investigated in order to identify differences in its protein patterns.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Listeria Monocytogenes Serotype 1/2a

TISSUE(S): Cell Culture

DISEASE(S): Listeriosis

SUBMITTER: Federica D'Onofrio

LAB HEAD: Maria Schirone

PROVIDER: PXD033519 | Pride | 2022-08-12

REPOSITORIES: Pride

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Immunoproteome profiling of Listeria monocytogenes under mild acid and salt stress conditions.

D'Onofrio Federica F Visciano Pierina P Krasteva Ivanka I Torresi Marina M Tittarelli Manuela M Pomilio Francesco F Iannetti Luigi L Di Febo Tiziana T Paparella Antonello A Schirone Maria M Luciani Mirella M

Proteomics 20220808 18

Listeria monocytogenes is one of the main foodborne pathogens worldwide. Although its response to stress conditions has been extensively studied, it is still present in the food processing environments and is a concern for consumers. To investigate how this microorganism adapts its proteome in mild stress conditions, a combined proteomics and bioinformatics approach was used to characterize the immunogenic protein profile of a sequence type 7 (ST7) strain that caused severe listeriosis outbreaks ...[more]

PMID: 35916071

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