Proteomics

Dataset Information

Spatial proteomics of selinexor, MK-2206 and combination response in AML cells

ABSTRACT: In order to characterize the dynamics of proteins between different cellular compartments in response to selinexor (XPO1 inhibitor), MK-2206 (Akt inhibitor) an the combination i AML cells, we treated MV4-11 and PL-21 cells for 6 hours with DMSO, 1 uM selinexor, 1 uM MK-2206 or the combination. Each condition was performed in 4 biological bio-reps.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Myeloblast, Leukemia Cell

DISEASE(S): Acute Leukemia

SUBMITTER: Kristina Bennet Emdal  

LAB HEAD: Jesper V. Olsen

PROVIDER: PXD033527 | Pride | 2022-08-07

REPOSITORIES: Pride

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Dataset's files

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20211229_EXPL1_Evo6_KBE_Collab_60spd_DIA_SubCell_Phospho_PL21_Combo_F1_R1_19.raw Raw
20211229_EXPL1_Evo6_KBE_Collab_60spd_DIA_SubCell_Phospho_PL21_Combo_F1_R2_43.raw Raw
20211229_EXPL1_Evo6_KBE_Collab_60spd_DIA_SubCell_Phospho_PL21_Combo_F1_R3_67.raw Raw
20211229_EXPL1_Evo6_KBE_Collab_60spd_DIA_SubCell_Phospho_PL21_Combo_F1_R4_91.raw Raw
20211229_EXPL1_Evo6_KBE_Collab_60spd_DIA_SubCell_Phospho_PL21_Combo_F2_R1_20.raw Raw
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