TET1 interactome by SILAC IP-MS in mouse ESCs

ABSTRACT: TET1 maintains hypomethylation at bivalent promoters through its catalytic activity in embryonic stem cells (ESCs). However, whether and how TET1 exerts catalytic activity-independent functions in regulating bivalent genes is not well understood. Therefore, we mapped the TET1 interactome in mouse ESCs using a SILAC IP-MS proteomics approach.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Embryonic Stem Cell

SUBMITTER: Xin Huang  

LAB HEAD: Jianlong Wang

PROVIDER: PXD033587 | Pride | 2022-06-10

REPOSITORIES: Pride