Proteomics

Dataset Information

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Sperm motility annotated genes: are they associated with impaired fecundity?


ABSTRACT: To determine whether Gene Ontology sperm motility annotated genes are differentially abundant in sperm collected from men with oligoasthenozoospermia and to gain further insight into molecular mechanisms underlying male infertility

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Spermatocyte

SUBMITTER: Markus Räschle  

LAB HEAD: Markus Räschle

PROVIDER: PXD033749 | Pride | 2023-07-20

REPOSITORIES: Pride

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Publications

Sperm Motility Annotated Genes: Are They Associated with Impaired Fecundity?

Abu-Halima Masood M   Becker Lea Simone LS   Al Smadi Mohammad A MA   Abdul-Khaliq Hashim H   Raeschle Markus M   Meese Eckart E  

Cells 20230425 9


Sperm motility is a prerequisite for achieving pregnancy, and alterations in sperm motility, along with sperm count and morphology, are commonly observed in subfertile men. The aim of the study was to determine whether the expression level of genes annotated with the Gene Ontology (GO) term 'sperm motility' differed in sperm collected from healthy men and men diagnosed with oligoasthenozoospermia. Reverse transcription quantitative real-time PCR (RT-qPCR), quantitative mass spectrometry (LC-MS/M  ...[more]

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