Insulin Resistance in a Type 1 Diabetes Rat Model

ABSTRACT: A automated 32-plex cPILOT chemical labeling strategy was utilized to identify proteome changes in type 1 diabetes in rats. We utilized an Orbitrap Fusion Lumos mass spectrometer to analyze 8 fractions in technical triplicates where proteins were quantified using Tandem Mass Tag pro reagents (16-plex reagents) and LC-SPS-MS3 acquisiton.

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Liver

SUBMITTER: Bailey Bowser  

LAB HEAD: Renã Robinson

PROVIDER: PXD033761 | Pride | 2025-05-26

REPOSITORIES: pride