Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Plasmodium Falciparum (isolate 3d7)
DISEASE(S): Plasmodium Falciparum Malaria
SUBMITTER: James Tuju
LAB HEAD: Prof Faith Osier
PROVIDER: PXD033964 | Pride | 2022-08-11
REPOSITORIES: Pride
Musasia Fauzia K FK Nkumama Irene N IN Frank Roland R Kipkemboi Victor V Schneider Martin M Mwai Kennedy K Odera Dennis O DO Rosenkranz Micha M Fürle Kristin K Kimani Domitila D Tuju James J Njuguna Patricia P Hamaluba Mainga M Kapulu Melissa C MC Wardemann Hedda H Osier Faith H A FHA
Nature communications 20220714 1
Ring-infected erythrocytes are the predominant asexual stage in the peripheral circulation but are rarely investigated in the context of acquired immunity against Plasmodium falciparum malaria. Here we compare antibody-dependent phagocytosis of ring-infected parasite cultures in samples from a controlled human malaria infection (CHMI) study (NCT02739763). Protected volunteers did not develop clinical symptoms, maintained parasitaemia below a predefined threshold of 500 parasites/μl and were not ...[more]