Identification of lysine-lactylated substrates in gastric cancer cells

ABSTRACT: Lysine lactylation is a newly discovered post-translational modification (PTM) in histones and plays important roles in regulating gene expression. However, Kla in non-histone proteins in mammal is still unclear. Here, an analysis of lactylated proteins in gastric cancer AGS cells by using LC-MS/MS was conducted, and 2375 Kla sites on 1014 proteins were identified.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Xianliang Ma  

LAB HEAD: Yongbin Ding

PROVIDER: PXD033991 | Pride | 2022-08-11

REPOSITORIES: Pride