IFI16 phase separation via multi-phosphorylation drives innate immune signaling

ABSTRACT: Fractionaion of nuclear periphery and core, followed by DDA in primary HFFs at 1 hour post infection with ICP0-RF HSV-1; IP-PRM of IFI16 in primary HFFs at 1 hpi; in vitro kinase assay with IFI16 and select kinases and quantification on phosphorlyated peptides by PRM.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Escherichia Coli

TISSUE(S): Cell Culture, Fibroblast

SUBMITTER: Dawei Liu  

LAB HEAD: Ileana Cristea

PROVIDER: PXD034348 | Pride | 2023-05-22

REPOSITORIES: Pride