Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Brian Mooney
LAB HEAD: Thomas E Spencer
PROVIDER: PXD034357 | Pride | 2023-10-11
REPOSITORIES: Pride
Fitzgerald Harriet C HC Kelleher Andrew M AM Ranjit Chaman C Schust Danny J DJ Spencer Thomas E TE
Molecular human reproduction 20230401 4
Uterine glands and, by inference, their secretions impact uterine receptivity, blastocyst implantation, stromal cell decidualization, and placental development. Changes in gland function across the menstrual cycle are primarily governed by the steroid hormones estrogen (E2) and progesterone (P4) but can also be influenced by extrinsic factors from the stroma. Using a human endometrial epithelial organoid system, transcriptome and proteome analyses identified distinct responses of the organoids t ...[more]