Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function.

ABSTRACT: Determination of the effect of the generic tyrosine kinase degrader TL12-186, and the BTK degraders DD-04-15 and DD-03-171 on human platelet protein content and function.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Platelet, Platelet, Blood Cell

SUBMITTER: Justin Trory  

LAB HEAD: Ingeborg Hers

PROVIDER: PXD034440 | Pride | 2023-03-02

REPOSITORIES: Pride