Quantitative proteomic analysis of cellular nuclear protein TMT markers from rat spinal cord tissue samples in neuropathic pain model

ABSTRACT: To further reveal the mechanism of neuropathic pain, we simulated neuropathic pain by constructing a chronic constriction injury of the sciatic nerve (CCI) model, followed by quantitative proteomic analysis of rat spinal cord cell nuclei at 1 day, 7 days and sham-operated groups after CCI. A total of 3 samples from each group were used. A total of 5039 proteins were identified in this study, of which 4469 proteins contained quantitative information. Differential proteins were defined by a threshold of change >1.3-fold and t-test p-value <0.05.v

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Spinal Cord

SUBMITTER: Zhifeng Huang  

LAB HEAD: Changsheng Huang

PROVIDER: PXD034960 | Pride | 2023-01-17

REPOSITORIES: Pride