Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Ovary
DISEASE(S): Malignant Neoplasm Of Ovary
SUBMITTER: Eva Borràs
LAB HEAD: Eduard Sabido
PROVIDER: PXD035084 | Pride | 2023-03-11
REPOSITORIES: Pride
Journal of translational medicine 20221221 1
<h4>Background</h4>High-grade serous carcinoma (HGSC) is the most common and deadly subtype of ovarian cancer. Although most patients will initially respond to first-line treatment with a combination of surgery and platinum-based chemotherapy, up to a quarter will be resistant to treatment. We aimed to identify a new strategy to improve HGSC patient management at the time of cancer diagnosis (HGSC-1LTR).<h4>Methods</h4>A total of 109 ready-available formalin-fixed paraffin-embedded HGSC tissues ...[more]