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Proteomic analysis of BioID experiments performed with Toxoplasma gondii MyoJ protein tagged with TurboID in tachyzoites

ABSTRACT: The aim of the project was to identify proteins of the basal complex of Toxoplasma gondii using MyoJ as bait

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Toxoplasma Gondii Rh

SUBMITTER: Dupuy Jean-William

LAB HEAD: Karine Frenal

PROVIDER: PXD035106 | Pride | 2022-11-01

REPOSITORIES: Pride

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Identification of new components of the basal pole of <i>Toxoplasma gondii</i> provides novel insights into its molecular organization and functions.

Roumégous Chloé C Abou Hammoud Aya A Fuster Damien D Dupuy Jean-William JW Blancard Corinne C Salin Bénédicte B Robinson Derrick R DR Renesto Patricia P Tardieux Isabelle I Frénal Karine K

Frontiers in cellular and infection microbiology 20221013

The <i>Toxoplasma gondii</i> tachyzoite is a singled-cell obligate intracellular parasite responsible for the acute phase of toxoplasmosis. This polarized cell exhibits an apical complex, a hallmark of the phylum Apicomplexa, essential for motility, invasion, and egress from the host cell. Located on the opposite end of the cell is the basal complex, an elaborated cytoskeletal structure that also plays critical roles in the lytic cycle of the parasite, being involved in motility, cell division, ...[more]

PMID: 36310866

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