Proteomics

Dataset Information

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Nuclear protein expression profiling of IMR90 RAS cells compared to IMR90 Control cells


ABSTRACT: One-third of all human cancers are attributable to mutations in RAS. Induction of oncogenic RAS during tumorigenesis leads to metabolic reprogramming and enhanced proliferation or senescence. These profound phenotypic changes require adaptations in gene expression, RNA processing, and protein synthesis. To investigate core drivers of this transformation, we analysed nuclear protein expression in IMR90 RAS cells and IMR90 Control cells 6 days after induction of HRASG12V.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Fibroblast

SUBMITTER: Alex Montoya  

LAB HEAD: Dr Pavel Shliaha

PROVIDER: PXD035299 | Pride | 2026-02-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Swissprot_human_9606_20190621.fasta Fasta
b008p086_EVN_1_rpt.raw Raw
b008p086_EVN_2_rpt.raw Raw
b008p086_EVN_3.raw Raw
b008p086_EVN_4.raw Raw
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