Proteomics

Dataset Information

Human Cardiovascular Tissue Extracellular Vesicles – Ultracentrifugation vs. Density Gradient

ABSTRACT: Fewer than 50% of patients develop vascular and valvular calcification, implying differential pathogenesis. Tissue-entrapped extracellular vesicles (EVs) are found in mineralization but their contents and functions are unstudied. Tissue EVs were isolated from normal and diseased human carotid arteries and aortic valves by enzymatic digestion, serial (ultra)centrifugation and density-gradient separation. Mass spectrometry characterized the density-gradient separation vs. ultracentrifugation.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Hathewaya Proteolytica Hathi

TISSUE(S): Aortic Valve, Carotid Atherosclerotic Plaque

SUBMITTER: Mark Blaser  

LAB HEAD: Elena Aikawa

PROVIDER: PXD035485 | Pride | 2023-07-10

REPOSITORIES: Pride

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Dataset's files

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Action DRS
02_FB_300TAV_2X_TopS_CID-IT_90min_5to21__UC_ExIod.raw Raw
02_FB_322TAV_2X_TopS_CID-IT_90min_5to21__UC_ExIod.raw Raw
02_FB_324TAV_fr1-4_2X_TopS_CID-IT_90min_5to21__ExIod.raw Raw
02_FB_328TAV_fr1-4_1X_TopS_CID-IT_90min_5to21__ExIod.raw Raw
02_FB_329TAV_fr1-4_1X_TopS_CID-IT_90min_5to21__ExIod.raw Raw
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