In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM

ABSTRACT: The spike protein of the porcine epidemic diarrhea virus from various strains was generated from different mammalian expression systems. The integration of cryo-EM and MS delineated the glycosylation patterns on Spike proteins and also helped understand how individual glycans contribute to biological functions.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Cell Culture

SUBMITTER: Yu-Chun Chien  

LAB HEAD: Kay-Hooi Khoo

PROVIDER: PXD035778 | Pride | 2022-10-15

REPOSITORIES: Pride