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Biosynthesis of membrane-spanning ether lipids in Thermotoga maritima.

ABSTRACT: This study was conducted to identify the proteins involved in the synthesis of membrane-spanning ether lipids in Thermotoga maritima.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Thermotoga Maritima Msb8

SUBMITTER: Sjef Boeren

LAB HEAD: Sjef Boeren

PROVIDER: PXD035794 | Pride | 2023-10-03

REPOSITORIES: Pride

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Publications

Disentangling the lipid divide: Identification of key enzymes for the biosynthesis of membrane-spanning and ether lipids in Bacteria.

Sahonero-Canavesi Diana X DX Siliakus Melvin F MF Abdala Asbun Alejandro A Koenen Michel M von Meijenfeldt F A Bastiaan FAB Boeren Sjef S Bale Nicole J NJ Engelman Julia C JC Fiege Kerstin K Strack van Schijndel Lora L Sinninghe Damsté Jaap S JS Villanueva Laura L

Science advances 20221216 50

Bacterial membranes are composed of fatty acids (FAs) ester-linked to glycerol-3-phosphate, while archaea have membranes made of isoprenoid chains ether-linked to glycerol-1-phosphate. Many archaeal species organize their membrane as a monolayer of membrane-spanning lipids (MSLs). Exceptions to this "lipid divide" are the production by some bacterial species of (ether-bound) MSLs, formed by tail-to-tail condensation of FAs resulting in the formation of (iso) diabolic acids (DAs), which are the l ...[more]

PMID: 36525503

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Biosynthesis of membrane-spanning ether lipids in Thermotoga maritima

Project description:This study was conducted to identify the genes involved in the synthesis of membrane-spanning ether lipids in Thermotoga maritima MSB8.

2022-10-26 | GSE211547 | GEO

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2021-09-10 | PXD024116 | Pride

Atmospheric hydrogen oxidation extends to the domain archaea

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Another layer of complexity in Staphylococcus aureus methionine biosynthesis control: Unusual RNase III-driven T-box riboswitch cleavage determines met operon mRNA stability and decay

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