Chemical Targeting of the Redox Switch in the Transcription Factor ΔFOSB

ABSTRACT: Purified protein fragments (~8 kDa bZIP domains, ΔFOSB and JunD) were reacted with individual compounds selected from a previous library screen. Reacted proteins were analyzed by LC-MS/MS peptide mapping and LC-MS intact mass analysis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell

DISEASE(S): Mixed Disorder As Reaction To Stress

SUBMITTER: Aaron Bailey  

LAB HEAD: Gabrielle Rudenko

PROVIDER: PXD035839 | Pride | 2022-10-14

REPOSITORIES: Pride