An isobaric quantitative crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and protein complexes

ABSTRACT: Experimental determination of protein conformational states is crucial to understand the mechanism of protein function and how function is altered in disease. We introduce a novel, simple and compact, isobaric crosslinker design for studying conformational and structural changes using quantitative mass spectrometry.

INSTRUMENT(S):

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Jie Luo  

LAB HEAD: Jeff Ranish

PROVIDER: PXD035939 | Pride | 2024-11-13

REPOSITORIES: Pride