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Campylobacter jejuni MOMP carbene footprinting

ABSTRACT: Using carbene footprinting, we map the MOMP-QPLEX interaction and show by complementary in silico docking that QPLEX enters the porin channel through interactions at the extracellular face, translocates down the channel through a dipole transverse electric field towards the opposite end and is released into the periplasm at the intracellular face of MOMP. Our studies suggest a potential mechanism for the non-antibiotic anti-Campylobacter activity of these ferric chelates.

INSTRUMENT(S):

ORGANISM(S): Campylobacter Jejuni Subsp. Jejuni Nctc 11168-po

SUBMITTER: Jeddidiah Bellamy-Carter

LAB HEAD: Neil J. Oldham

PROVIDER: PXD035978 | Pride | 2022-09-26

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	File_tree.txt	Txt
	JBC_MOMP_ctrl_10qplex.csv	Csv
	JBC_MOMP_ctrl_10qplex.pfoot	Other
	JBC_MOMP_ctrl_40qplex.csv	Csv
	JBC_MOMP_ctrl_40qplex.pfoot	Other

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