Proteomics

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One-pot comparative analysis and characterization of MCF-7 and MCF-10A cell lines


ABSTRACT: A comparison of different energetics based techniques for the characterization of two mammalian breast cell lines, MCF-7 a luminal A breast cancer cell line and MCF-10A a normal human breast cell line. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Morgan Bailey  

LAB HEAD: Michael C. Fitzgerald

PROVIDER: PXD036268 | Pride | 2023-02-22

REPOSITORIES: Pride

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