One-pot comparative analysis and characterization of MCF-7 and MCF-10A cell lines
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ABSTRACT: A comparison of different energetics based techniques for the characterization of two mammalian breast cell lines, MCF-7 a luminal A breast cancer cell line and MCF-10A a normal human breast cell line. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed.
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Breast Cancer
SUBMITTER: Morgan Bailey
LAB HEAD: Michael C. Fitzgerald
PROVIDER: PXD036268 | Pride | 2023-02-22
REPOSITORIES: Pride
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