Proteomics

Dataset Information

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Venomics of Iranian and Cypriot Macrovipera lebetina


ABSTRACT: the venom proteomes of Macrovipera lebetina lebetina from Cyprus and Macrovipera lebetina cernovi from Iran were characterized using bottom-up proteomics.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Macrovipera Lebetina

TISSUE(S): Venom

SUBMITTER: Parviz Ghezellou  

LAB HEAD: Bernhard Spengler

PROVIDER: PXD036466 | Pride | 2023-03-11

REPOSITORIES: Pride

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Publications

Comparative Venom Proteomics of Iranian, <i>Macrovipera lebetina cernovi</i>, and Cypriot, <i>Macrovipera lebetina lebetina</i>, Giant Vipers.

Ghezellou Parviz P   Dillenberger Melissa M   Kazemi Seyed Mahdi SM   Jestrzemski Daniel D   Hellmann Bernhard B   Spengler Bernhard B  

Toxins 20221020 10


Envenoming by Macrovipera lebetina subspecies causes severe life-threatening difficulties for people living in North Africa and the Middle East. To better understand the pathophysiology of envenoming and improve patient management, knowledge about the venom components of the subspecies is essential. Here, the venom proteomes of Macrovipera lebetina lebetina from Cyprus and Macrovipera lebetina cernovi from Iran were characterized using RP-HPLC separation of the crude venom proteins, SDS-PAGE of  ...[more]

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