Ontology highlight
ABSTRACT:
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Liver
SUBMITTER: Wu shengxian
LAB HEAD: Shengxian Wu
PROVIDER: PXD036478 | Pride | 2023-03-11
REPOSITORIES: Pride
Li He H Du Yawei Y Ji Hanrui H Yang Yanan Y Xu Changchang C Li Qiaodan Q Ran Longkai L Wu Chongming C Zhou Qile Q Wu Shengxian S
iScience 20220926 11
<i>Ganoderma lucidum</i> is a traditional Chinese medicine with a variety of active compounds and possesses adequate lipid-lowering and anti-atherosclerotic effects. However, its main active components and potential mechanisms still remain unclear. Here, we evaluated the anti-hyperlipidemic effect of the adenosine extract from <i>Ganoderma lucidum</i> (AEGL) in high-fat-diet (HFD)-induced hyperlipidemic ApoE<sup>-/-</sup> mice and explored the underlying biological mechanism by multi-omics analy ...[more]