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Characterization of a cyanobacterial exoproteome reveals a novel zinc acquisition system used by primitive bacteria

ABSTRACT: Zinc can be limiting in many environments and bacteria have developed acclimation responses to counteract this deficiency. In most bacteria, the acclimation response to zinc limitation is controlled by Zur, a transcriptional regulator of the FUR family. Several proteins that take part in this response are present in the cytoplasm and the cell envelope. However, little is known about the involvement of proteins present in the extracellular space in the response to Zn limitation and whether the protein composition of this space might be also regulated by Zur. Therefore, in order to get an insight into these issues, a comparative analysis of the exoproteomes of the cyanobacterium Anabaena sp. PCC7120 (WT) and its Δzur derivative strain (referred as "MN" in the present dataset) was carried out using SWATH-MS analysis.

INSTRUMENT(S): TripleTOF 5600+

ORGANISM(S): Nostoc Sp. (strain Pcc 7120 / Utex 2576)

SUBMITTER: Cristina Sarasa Buisán

LAB HEAD: Ignacio Luque

PROVIDER: PXD036795 | Pride | 2024-02-15

REPOSITORIES: Pride

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