Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Stem Cell, Cell Culture
DISEASE(S): Breast Cancer
SUBMITTER: Eugene C Yi
LAB HEAD: Eugene C. Yi
PROVIDER: PXD036909 | Pride | 2023-10-24
REPOSITORIES: Pride
Seo Yu Ri YR Lee Junghyeon J Ryu Han Suk HS Kim EunHee G EG Kim So Hyun SH Jeong Jieun J Jung Hyeryeon H Jung YeoJin Y Kim Han Byeol HB Jo Yeon Hui YH Kim Yeong Dong YD Jin Min-Sun MS Lee Yong Yook YY Kim Kristine M KM Yi Eugene C EC
Scientific reports 20230830 1
Oncogenic cell-surface membrane proteins contribute to the phenotypic and functional characteristics of cancer stem cells (CSCs). We employed a proximity-labeling proteomic approach to quantitatively analyze the cell-surface membrane proteins in close proximity to CD147 in CSCs. Furthermore, we compared CSCs to non-CSCs to identify CSC-specific cell-surface membrane proteins that are closely interact with CD147 and revealed that lateral interaction between CD147 and CD276 concealed within the li ...[more]