Proteomics

Dataset Information

Proteolytic processing of galectin-3 is crucial for host microbiome homeostasis

ABSTRACT: To identify relevant substrates for meprin α/β heterodimers, we applied mass spectrometry-based N-terminomics of mouse colon tissue as well as of human Caco-2 cells and identified galectin-3 as a novel intestinal substrate. The proteolytic processing of galectin-3 by meprin α/β heterodimers plays a key role in the maintenance of the host-microbiome homeostasis within the colon.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Colon

SUBMITTER: Andreas Tholey  

LAB HEAD: Andreas Tholey

PROVIDER: PXD037000 | Pride | 2023-05-10

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
A9_04022022_m1_0_CHY.pdResult Other
A9_04022022_m1_0_CHY.raw Raw
A9_04022022_m1_0_TRY.pdResult Other
A9_04022022_m1_0_TRY.raw Raw
A9_04022022_m2_0_CHY.pdResult Other
Items per page:
1 - 5 of 70
altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets