Proteomics,N-glycoproteomics and Phosphoproteomics of SARS-Cov-2 Infected Calu-3 Cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
SUBMITTER: 
Rui Chen
LAB HEAD: Rui Chen
PROVIDER: PXD037097 | Pride | 2024-01-26
REPOSITORIES: Pride
Publications
Integrated Immunopeptidomics and Proteomics Study of SARS-CoV-2-Infected Calu-3 Cells Reveals Dynamic Changes in Allele-specific HLA Abundance and Antigen Presentation.
Chen Rui R Fulton Kelly M KM Tran Anh A Duque Diana D Kovalchik Kevin K Caron Etienne E Twine Susan M SM Li Jianjun J
Molecular & cellular proteomics : MCP 20230913 10
We present an integrated immunopeptidomics and proteomics study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to comprehensively decipher the changes in host cells in response to viral infection. Immunopeptidomics analysis identified viral antigens presented by host cells through both class I and class II MHC system for recognition by the adaptive immune system. The host proteome changes were characterized by quantitative proteomics and glycoproteomics and from these ...[more]
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