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Cryo-EM study of bovine retinal pigment epithelium cell lysate

ABSTRACT: This is the proteomic analysis data of bovine retinal pigment epithelium cell lysate subjected to cryo-EM study.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Epithelial Cell, Retinal Pigment Epithelium Cell

SUBMITTER: zhemin zhang

LAB HEAD: Edward W. Yu

PROVIDER: PXD037186 | Pride | 2023-01-02

REPOSITORIES: Pride

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Toward structural-omics of the bovine retinal pigment epithelium.

Morgan Christopher E CE Zhang Zhemin Z Miyagi Masaru M Golczak Marcin M Yu Edward W EW

Cell reports 20221201 13

The use of an integrated systems biology approach to investigate tissues and organs has been thought to be impracticable in the field of structural biology, where the techniques mainly focus on determining the structure of a particular biomacromolecule of interest. Here, we report the use of cryoelectron microscopy (cryo-EM) to define the composition of a raw bovine retinal pigment epithelium (RPE) lysate. From this sample, we simultaneously identify and solve cryo-EM structures of seven differe ...[more]

PMID: 36577381

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