Proteomics

Dataset Information

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LFQ proteomics analysis of M. smegmatis treated with BacPROTACs.


ABSTRACT: To monitor selective degradation of ClpC1 and ClpC2 using BacPROTAC compounds in M. smegmatis we performed a LFQ proteomics analysis treating the cells at bactericidal compound concentration. We detected degradation of both proteins and additional dysregulation of the mycobacterial PQC system.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Mycobacterium Smegmatis (strain Atcc 700084 / Mc(2)155)

SUBMITTER: David Hoi  

LAB HEAD: Markus Hartl

PROVIDER: PXD037235 | Pride | 2023-06-07

REPOSITORIES: Pride

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