Proteomic profile of extracellular vesicles released by breast cancer cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Permanent Cell Line Cell
DISEASE(S): Breast Cancer
SUBMITTER: 
Marco Gaspari
LAB HEAD: Marco Gaspari
PROVIDER: PXD037266 | Pride | 2023-03-11
REPOSITORIES: Pride
Publications
Proteomic Profiling of Extracellular Vesicles Released by Leptin-Treated Breast Cancer Cells: A Potential Role in Cancer Metabolism.
Gelsomino Luca L Barone Ines I Caruso Amanda A Giordano Francesca F Brindisi Matteo M Morello Giovanna G Accattatis Felice Maria FM Panza Salvatore S Cappello Anna Rita AR Bonofiglio Daniela D Andò Sebastiano S Catalano Stefania S Giordano Cinzia C
International journal of molecular sciences 20221026 21
Tumor extracellular vesicles (EVs), as endocytic vesicles able to transport nucleic acids, proteins, and metabolites in recipient cells, have been recognized fundamental mediators of cell-to-cell communication in breast cancer. The biogenesis and release of EVs are highly regulated processes and both the quantity of EVs and their molecular cargo might reflect the metabolic state of the producing cells. We recently demonstrated that the adipokine leptin, whose circulating levels correlate with ad ...[more]
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