Proteomics

Dataset Information

0

Proteomics profiling in primary tumors of metastatic and non-metastatic breast cancers


ABSTRACT: Analysis of different proteomics profile in primary tumors of metastatic and non-metastatic breast cancers.

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Mus Musculus (mouse)

DISEASE(S): Breast Cancer

SUBMITTER: Animesh Sharma  

LAB HEAD: Kristine Pettersen

PROVIDER: PXD037288 | Pride | 2023-03-09

REPOSITORIES: Pride

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Publications

Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer.

Lamsal Apsana A   Andersen Sonja Benedikte SB   Johansson Ida I   Vietri Marina M   Bokil Ansooya Avinash AA   Kurganovs Natalie Jayne NJ   Rylander Felicia F   Bjørkøy Geir G   Pettersen Kristine K   Giambelluca Miriam S MS  

Cell communication and signaling : CCS 20230307 1


<h4>Background</h4>To our current understanding, solid tumors depend on suppressed local immune reactions, often elicited by the interaction between tumor cells and tumor microenvironment (TME) components. Despite an improved understanding of anti-cancer immune responses in the TME, it is still unclear how immuno-suppressive TME are formed and how some cancer cells survive and metastasize.<h4>Methods</h4>To identify the major adaptations that cancer cells undergo during tumor development and pro  ...[more]

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